摘要 |
3 - Unsubstituted 6 - chloro - D 3,5 - steroids of the androstane, estrane and pregnane series are prepared by chlorinating a corresponding 3,5-cyclo-steroid to give a 3b ,5-dichloro-D 5-intermediate, hydrolysing in an acid medium and ketal groups present, and dehydrohalogenating. |