发明名称 |
COMBINATION OF VEGF RECEPTOR TYROSINE KINASE INHIBITORS FOR TREATMENT OF CANCER |
摘要 |
<p>The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of a cancer, particularly a cancer involving a solid tumor, which comprises the administration of ZD6474 in combination with ZD1839; to a pharmaceutical composition comprising ZD6474 and ZD1839; to a combination product comprising ZD6474 and ZD1839 for use in a method of treatment of a human or animal body by therapy; to a kit comprising ZD6474 and ZD1839; to the use of ZD6474 and ZD1839 in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation.</p> |
申请公布号 |
WO2004014426(A1) |
申请公布日期 |
2004.02.19 |
申请号 |
WO2003GB03390 |
申请日期 |
2003.08.05 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;WEDGE, STEPHEN, ROBERT |
发明人 |
WEDGE, STEPHEN, ROBERT |
分类号 |
A61K31/517;A61K45/06;A61P9/00;A61P35/00;(IPC1-7):A61K45/00 |
主分类号 |
A61K31/517 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|