发明名称 |
BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM |
摘要 |
<p>The present invention provides a method for treating diseases caused by and/or associated with an altered protein kinase activity which comprises administering to a mammal in need thereof an effective amount of a pyrazole-tetrahydro pyridine derivative. The invention also provides specific pyrazole-tetrahydro pyridines, a library comprising at least two of them, a process for their preparation and the pharmaceutical compositions containing them, which are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, viral infections, autoimmune diseases and neurodegenerative disorders.</p> |
申请公布号 |
WO2004014374(A1) |
申请公布日期 |
2004.02.19 |
申请号 |
WO2003EP07000 |
申请日期 |
2003.07.01 |
申请人 |
PHARMACIA ITALIA S.P.A.;VILLA, MANUELA;ABRATE, FRANCESCA;FANCELLI, DANIELE;VARASI, MARIO;VULPETTI, ANNA |
发明人 |
VILLA, MANUELA;ABRATE, FRANCESCA;FANCELLI, DANIELE;VARASI, MARIO;VULPETTI, ANNA |
分类号 |
A61P11/00;A61K31/437;A61P9/10;A61P13/08;A61P13/12;A61P17/06;A61P19/02;A61P25/00;A61P25/28;A61P31/12;A61P35/00;A61P35/04;A61P37/02;A61P43/00;C07D471/04;(IPC1-7):A61K31/437 |
主分类号 |
A61P11/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|