发明名称 |
Compositions and methods for treatment of Hepatitis C virus-associated diseases |
摘要 |
Antisense oligonucleotides are provided which are complementary to and hybridizable with at least a portion of HCV RNA and which are capable of inhibiting the function of the HCV RNA. These oligonucleotides can be administered to inhibit the activity of Hepatitis C virus in vivo or in vitro. These compounds can be used either prophylactically or therapeutically to reduce the severity of diseases associated with Hepatitis C virus, and for diagnosis and detection of HCV and HCV-associated diseases. Methods of using these compounds are also disclosed.
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申请公布号 |
US2004033978(A1) |
申请公布日期 |
2004.02.19 |
申请号 |
US20030457304 |
申请日期 |
2003.06.09 |
申请人 |
ANDERSON KEVIN P.;HANECAK RONNIE C.;NOZAKI CHIKATERU;DORR F. ANDREW;KWOH T. JESSE |
发明人 |
ANDERSON KEVIN P.;HANECAK RONNIE C.;NOZAKI CHIKATERU;DORR F. ANDREW;KWOH T. JESSE |
分类号 |
A61K31/70;C12N15/09;A61P31/12;C07H21/00;C07H21/04;C07K14/18;C12N5/10;C12N15/113;C12P21/02;C12Q1/68;C12Q1/70;G01N33/53;G01N33/576;(IPC1-7):A61K48/00;C07H21/02 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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