Method for the production of phyllanthus extracts

摘要

A method for the production of an extract of Phyllanthus wherein (a) Phyllanthus components are extracted with an ethanol/water mixture of 5-85% m/m to which a heavy-metal chelator is added at a concentration of 0.001-3% m/m; (b) the primary extract obtained in step (a) is contacted and concentrated with (ba) Indian Sterculia gum at a final concentration of 0.5-5.0% mm relative to the sum of the extractive substances or (bb) one or more polymers and impendable and/or soluble substance(s); and (c) the concentrated extract obtained in step (b) is dried. The method according to the invention leads to particularly high yield of pharmaceutically effective plant ingredients and is thus of particular interest for therapeutic applications. In a preferred embodiment of the invention the method according to the invention includes a filtration step of the primary extract. It is further preferred that a lipoid is added during the extraction method. The Phyllanthus Phyllanthus amarus is preferred. Moreover, the invention relates to pharmaceutical compositions containing the extracts obtained by the method of the invention