| 摘要 |
Fluoroalkanes such as fluoromethane labeled with <17>F are produced by contacting <17>F labeled F2 with alkanes, preferably methane, substituted or unsubstituted alkenes, or substituted or unsubstituted alkynes in the presence of a metal oxide catalyst, preferably a silver oxide catalyst, to produce the <17>F labeled fluoroalkane. The <17>F may be produced by irradiating <20>Ne with protons, preferably having an energy of about 11 MeV and produced by a cyclotron. The <17>F labeled fluoromethane or fluoroalkanes may be produced continuously. A method for determining the location of an <17>F labeled tracer includes generating an <17>F labeled fluoroalkane, administering the <17>F labeled fluoroalkane to a test subject, and scanning the test subject with a radiosensitive detector such as a positron emission tomography scanner.
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