发明名称 |
Novel imidazole derivatives, production method thereof and use thereof |
摘要 |
The present invention provides a compound having a steroid C17,20-lyase-inhibitory activity and useful for the therapy and prophylaxis of tumor such as prostatism, breast cancer and the like, and a method for efficiently separating an optically active compound of this compound from a mixture of optical isomers thereof, a compound of the formula: wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof, and a method for obtaining an optically active compound by optically resolving a mixture of optical isomers by the use of a resolving agent such as tartranilic acid and the like.
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申请公布号 |
US2004033935(A1) |
申请公布日期 |
2004.02.19 |
申请号 |
US20030416986 |
申请日期 |
2003.05.16 |
申请人 |
TASAKA AKIHIRO;HITAKA TAKENORI;MATSUNAGA NOBUYUKI;KUSAKA MASAMI;ADACHI MARI;OAKI ISAO;OJIDA AKIO |
发明人 |
TASAKA AKIHIRO;HITAKA TAKENORI;MATSUNAGA NOBUYUKI;KUSAKA MASAMI;ADACHI MARI;OAKI ISAO;OJIDA AKIO |
分类号 |
C07D233/62;A61K31/165;A61K31/4174;A61K31/4188;A61K31/437;A61K45/00;A61P5/28;A61P35/00;A61P43/00;C07D233/54;C07D471/04;C07D487/04;(IPC1-7):A61K31/00 |
主分类号 |
C07D233/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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