发明名称 SUBSTITUTED BENZIMIDAZOLE COMPOUNDS
摘要 Disclosed are substituted benzimidazole compounds of formula (I) wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and th e pharmaceutical compositions comprising these compounds.
申请公布号 CA2494942(A1) 申请公布日期 2004.02.19
申请号 CA20032494942 申请日期 2003.08.01
申请人 BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 发明人 MORIARITY, KEVIN J.;WANG, JI;NEMOTO, PETER ALLEN;QIAO, LEI;PULLEN, STEVEN S.;SNOW, ROGER JOHN;FLECK, ROMAN WOLFGANG;COOK, BRIAN NICHOLAS;CYWIN, CHARLES L.;TAKAHASHI, HIDENORI;LO, HO-YIN;WINTERS, MICHAEL;BENTZIEN, JOERG MARTIN;ROTH, GREGORY PAUL
分类号 A61K31/4184;A61K39/00;A61P1/04;A61P3/10;A61P11/00;A61P11/06;A61P11/08;A61P17/00;A61P17/06;A61P25/00;A61P27/02;A61P27/16;A61P29/00;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D235/28;C07D235/30;C07D409/12;(IPC1-7):C07D417/12 主分类号 A61K31/4184
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