FEEDBACK CONTROL DEVICE FOR TRANSCUTANEOUS DRUG DELIVERY AND USES THEREFOR

摘要

Provided herein is a device for altering a biological membrane in an individual comprising a means for delivering energy (2) to the surface of said biological membrane (7); a means for monitoring a physiological state of said biological membrane (7) during delivery of said energy; a means for modulating delivery of said energy (12) to said biological membrane (7) wherein said modulating is in response to a change in said monitored physiological state; and a housing means for said device. Also provided is a device to control the permeation of substance across a biological membrane and methods for use of these devices.