发明名称 Combination containing N-(5-[4-(4-methyl-piperazino-methyl)benzoylamido]-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidin-amine intended for the treatment of proliferative diseases
摘要 <p>A method of treating a warm-blooded animal, especially a human, having a proliferative disease or acute or chronic transplant rejection comprising administering to the animal a combination which comprises (a) N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and (b) a chemotherapeutic agent selected from antineoplastic agents, especially as defined herein, and agents effective in treating acute or chronic transplant rejection; a combination comprising (a) and (b) as defined above and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, in particular for the delay of progression or treatment of a proliferative disease, especially a solid tumor disease.</p>
申请公布号 CZ20033098(A3) 申请公布日期 2004.02.18
申请号 CZ20030003098 申请日期 2002.05.15
申请人 NOVARTIS AG 发明人 BRUNS CHRISTIAN;BUCHDUNGER ELISABETH;O REILLY TERENCE;SILBERMAN SANDRA LETA;WARTMANN MARKUS;WECKBECKER GISBERT
分类号 A61K45/00;A61K31/506;A61K31/675;A61K45/06;A61P35/00;A61P35/04;A61P37/06;A61P43/00;(IPC1-7):A61K31/506 主分类号 A61K45/00
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