发明名称 Novel piperidine carboxamide derivatives, process of their preparation and pharmaceutical compositions in which the derivatives are comprised
摘要 <p>The invention relates to compounds of formula (I): as well as their salts with inorganic or organic acids, their solvates and/or their hydrates, which exhibit a very high affinity both for the human NK<SUB>2 </SUB>receptors for neurokinin A and for the human NK<SUB>3 </SUB>receptors for neurokinin B and are antagonists of the said receptors. The invention also relates to their method of preparation, the pharmaceutical compositions containing them and their use for the preparation of medicaments.</p>
申请公布号 CZ20033132(A3) 申请公布日期 2004.02.18
申请号 CZ20030003132 申请日期 2002.05.17
申请人 SANOFI-SYNTHELABO 发明人 EMONDSALT XAVIER;PROIETTO VINCENZO
分类号 A61K31/5377;A61P1/00;A61P1/02;A61P1/04;A61P3/04;A61P3/10;A61P7/02;A61P7/10;A61P9/00;A61P9/08;A61P9/10;A61P9/14;A61P11/00;A61P11/02;A61P11/06;A61P11/08;A61P13/00;A61P13/02;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P17/16;A61P19/02;A61P19/04;A61P21/00;A61P21/02;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P27/02;A61P29/00;A61P29/02;A61P31/10;A61P31/18;A61P35/00;A61P35/04;A61P37/00;A61P37/04;A61P37/06;A61P37/08;A61P43/00;C07D413/06;(IPC1-7):C07D413/14;A61K31/537;A61K31/452 主分类号 A61K31/5377
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