发明名称 |
Recombinant human SM-11044-binding receptor proteins exhibiting ligand-binding activities, and their use |
摘要 |
Transformed cells designed to express a recombinant human SMBP at an elevated level to the extent that its ligand-binding activity can be measured, and cellular membrane fractions thereof; recombinant human SMBPs isolated from the transformed cells or the cellular membrane fractions thereof; a screening system for human SMBP agonists/antagonists characterized by utilizing the transformed cells, the cellular membrane fractions thereof or the isolated recombinant human SMBPs; and human SMBP agonists or antagonists obtainable by the screening system, are provided by deleting the polythymidine sequence from the base sequence of the 3'-untranslated region.
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申请公布号 |
US6692926(B1) |
申请公布日期 |
2004.02.17 |
申请号 |
US20010786681 |
申请日期 |
2001.04.30 |
申请人 |
SUMITOMO PHARMACEUTICALS COMPANY, LIMITED |
发明人 |
SUGASAWA TOSHINARI;HIDAKA JUN;KAWAKAMI HAJIME |
分类号 |
A61K38/00;C07K14/705;(IPC1-7):C07K1/00;C07H21/04;C12N1/20;C12P21/06;G01N33/566 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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