| 摘要 |
<p>The present invention relates to thiolalkyl benzoic acids of the Formulae (Ia), (Ib) and (I) (in which the variables are as defined in the claims), pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-beta activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers, glaucoma and retinal disorders.</p> |
