A immounlogical epitope of the hiv strain type o and the uses thereof

摘要

The present invention relates to a new immounlogical epitope of the HIV strain Type O and the uses thereof. The present invention provides a new immounlogical epitope of the HIV strain Type O. The N-end of the epitope is asparagine, its C-end is two adjacent residues of glutamic acid. The N-end of the epitope being consist of two amino acid residues usually links with the leucine residue. The C-end of the epitope usually ligates to the tryptophan residue. The amino acid sequence of the immounlogical epitope is LDEW. Based on the sequence, the N-end of it usually ligates to the glutamic acid residue. The C-end of it usually links with the alanine residue, So the amino acid sequence of the immounlogical epitope is ELDEWA. The epitope can be used as target for the identification and diagnosis of the HIV-1 Type O, also as target for drugs.