发明名称 |
METHOD OF DEUBIQUITINATION |
摘要 |
The invention concerns a new class of deubiquitinating enzymes and methods of deubiquitination using these enzymes or functional fragments or derivates thereof. In one aspect, the invention covers a method for enzymatic deubiquitination of a molecule which has been ubiquitinated to form a ubiquitinated molecule, comprising the step of contacting the ubiquitinated molecule with an enzyme, wherein the enzyme or a domain thereof has at least 20% amino acid sequence identity with the TRAFB domain defined by Cezanne amino acid residues 160-416 (SEQ ID NO:1). |
申请公布号 |
AU2003251363(A1) |
申请公布日期 |
2004.02.16 |
申请号 |
AU20030251363 |
申请日期 |
2003.07.31 |
申请人 |
THE BABRAHAM INSTITUTE |
发明人 |
PETER, JOHN KILSHAW;PAUL, CHARLES EVANS |
分类号 |
C07K14/47;C12N9/64;C12N15/57;C12P21/06 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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