发明名称 |
Enteric coated stable oral pharmaceutical composition of acid unstable drug and process for preparing the same |
摘要 |
Enteric coated stable oral pharmaceutical composition of acid unstable drug. The enteric coating is a bilayer with a pH gradient across its thickness comprising an inner layer of neutral or near neutral pH 7-7.5 and an outer layer of acidic pH 2-6. Also process for preparng the enteric coated stable oral pharmaceutical composition of acid unstable drug. The enteric coating is first carried out at neutral or near neutral pH of 7-7.5 to form an inner layer of neutral or near neutral pH and then at acidic pH of 2-6 to form an outer layer of acidic pH.
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申请公布号 |
US2004028737(A1) |
申请公布日期 |
2004.02.12 |
申请号 |
US20020216315 |
申请日期 |
2002.08.12 |
申请人 |
KOPRAN RESEARCH LABORATORIES LIMITED |
发明人 |
DESHPANDE JAYANT VENKATESH;GUPTE VANDANA SANDEEP;KADAM VAISHALI MADHUKAR;GOSAR CHANDRAKANT THAKARSI;DESHMUKH SATISH RAMACHANDRA;GUPTE RAJAN VITTHAL;TAMHANKAR VIJAY RAMACHANDRA |
分类号 |
A61K9/28;A61K9/50;A61K31/4439;(IPC1-7):A61K31/443;A61K9/16 |
主分类号 |
A61K9/28 |
代理机构 |
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