Antisense compounds, compositions and methods are provided for modulating the expression of human FXR. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding human FXR. Methods of using these compounds for modulation of human FXR expression and for treatment of diseases associated with expression of human FXR are provided.
申请公布号
WO03044167(A3)
申请公布日期
2004.02.12
申请号
WO2002US36691
申请日期
2002.11.13
申请人
ISIS PHARMACEUTICALS, INC.;MONIA, BRETT, P.;WATT, ANDREW, T.