NEOVASCULARIZATION INHIBITOR AND ITS UTILIZATION

摘要

PROBLEM TO BE SOLVED: To obtain a neovascularization inhibitor capable of strongly suppressing neovascularization which occurs together with progress of various diseases, and a composition capable of industrially effectively utilizing the inhibitor.

SOLUTION: The neovascularization inhibitor comprises a glutamic anhydride represented by formula (1) and/or its derivative as an active ingredient and the glutamic anhydride is preferably an L type and the glutamic anhydride is preferably a salt or an amide. The glutamic anhydride and the glutamic anhydride derivative are each chemically synthesized or they are each applicable as an extract or a purified product obtained by extracting mushrooms such as a mushroom of the genus Agaricus with a hydrophilic organic solvent and a hydrophobic organic solvent. The composition is obtained by formulating the neovascularization inhibitor and is utilized as a food product or beverage or a medicine in order to activate immunization and suppress tumors and prevent and treat various diseases.

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