METHOD FOR THE PRODUCTION OF (S)-3-METHYLAMINO-1-(THIEN-2-YL)PROPAN-1-OL

摘要

The invention relates to a method for the production of enantiomer-pure (S)- 3- methylamino-1-(thien-2-yl)propan-1-ol of formula (II-S) by obtaining (S)-3- hydroxy-3-thien-2-ylproipionitril from its enantiomer mixture with the R- isomer and by subsequently reacting (S)-3-hydroxy-3-thien-2-ylpropionitril with hydrogen and methylamine in the presence of a catalyst in order to obta in (II-S).