NF-kappaB inhibitor comprising phenylmethyl benzoquinone as an active ingredient

摘要

An NF-kappaB inhibitor having as an active ingredient a benzoquinone derivative represented by the general formula (1) wherein R<1>, R<2>, and R<3 >are each independently H, alkyl having 1 to 5 carbons, or alkoxy having 1 to 5 carbons; R4 is H, hydroxymethyl, alkyl, or carboxyl which is optionally esterified or amidated; Z is represented by the formula (A); and, n is an integer from 0 to 6, or its hydroquinone form or a pharmaceutically acceptable salt thereof.