发明名称 |
TREATMENT OF MULTIPLE SCLEROSIS WITH BRAIN TARGETED ANTI OXIDANT COMPOUNDS |
摘要 |
A method of treating multiple sclerosis, the method comprises administering to a subject in need thereof a therapeutically effective amount of a compound, the compound having: (a) a combination of molecular weight and membrane miscibility properties for permitting the compound to cross the blood brain barrier of the organism; (b) a readily oxidizable chemical group for exertin g antioxidation properties; and (c) a chemical make-up for permitting the compound or its intracellular derivative to accumulate within the cytoplasm of cells.
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申请公布号 |
CA2494503(A1) |
申请公布日期 |
2004.02.12 |
申请号 |
CA20032494503 |
申请日期 |
2003.07.31 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALE M</;RAMOT AT TEL-AVIV INIVERSITY LTD.;MOR RESEARCH APPLICATIONS LTD. |
发明人 |
OFFEN, DANIEL;ATLAS, DAPHNE;MELAMED, ELDAD |
分类号 |
A61K31/00;(IPC1-7):A61K31/225;A61K31/195;A61K31/22 |
主分类号 |
A61K31/00 |
代理机构 |
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