| 摘要 |
<P>PROBLEM TO BE SOLVED: To obtain a broad spectrum cephem compound which exhibits a broad anti-bacterial spectrum against various sensitive bacteria and is also effective against MRSA (multi-resistant Staphylococus aureus). <P>SOLUTION: This compound is represented by formula (I) (X is N, CH or CCl; R<SP>1</SP>is amino or a protected amino; R<SP>2</SP>is H, a lower alkyl which may be substituted, or the like; R<SP>3</SP>is H, or the like; R<SP>4</SP>is an amino lower alkyl which may be substituted, an N atom-containing heterocyclic group which may be substituted, or the like; R<SP>5</SP>is H or the like; the waved line exhibits syn-, anti- or their mixture), its ester or pharmaceutically acceptable salt, or their hydrates. <P>COPYRIGHT: (C)2004,JPO |
