发明名称 ANTISENSE MODULATION OF PROTEIN EXPRESSION
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of H-Ras, WNT-7B, acetylglucosaminyltransferase, voltage-gated K chananel, IL-8, ion transport, Map3K8 and Thymidine kinase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids ancoding H-Ras, WNT-78, acetylglucosaminyltransferase, voltage-gated K channel, IL-8, ion transport, Map3K8 and Thymidine kinase. Methods of using these compounds for modulation of H-Ras, WNT-7B, acetylglucosaminyltransferase, voltage-gated K channel, IL-8, ion transport, Map3K8 and Thymidine kinase expression and for treatment of diseases associated with expression of H-Ras, WNT-7B, acetylglucosaminyltransferase, voltage-gated K channel, IL-8, io n transport, Map3K8 and Thymidine kinase are provided.
申请公布号 WO03070160(A3) 申请公布日期 2004.02.12
申请号 WO2002US38188 申请日期 2002.11.27
申请人 CURAGEN CORPORATION;JU, JINGFANG;HUANG, CHUNLI;ZHONG, HAIHONG;SIMONS, JAN, FREDIK;TAILLON, BRUCE, E.;CHANT, JOHN, S.;PEYMAN, JOHN, A.;SMITHSON, GLENNDA;MILLET, ISABELLE 发明人 JU, JINGFANG;HUANG, CHUNLI;ZHONG, HAIHONG;SIMONS, JAN, FREDIK;TAILLON, BRUCE, E.;CHANT, JOHN, S.;PEYMAN, JOHN, A.;SMITHSON, GLENNDA;MILLET, ISABELLE
分类号 C12N15/113 主分类号 C12N15/113
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