发明名称 NON-TOXIC AMOUNTS OF PROTEIN-AGGREGATING SUBSTANCES STIMULATE HSP70 EXPRESSION AND FUNCTION AS ANTI-TUMOR AGENTS
摘要 The present invention relates to the use of a drug inducing intracellular protein aggregation for the preparation of a pharmaceutical composition wherein the drug is in a dose of 135-175 mg/m2 body surface for the treatment of a tumor, a bacterial infection or a viral infection. Preferably said drug is selected from vincristine and paclitaxel. The present invention further relates to a method, of treating a patient suffering from a tumor, a bacterial infection or a viral infection comprising administering to said patient a drug inducing intracellular protein aggregation in a dose of 135-175 mg/m<2 >body surface. It is preferred that said drug is administered in combination with heat treatment.
申请公布号 WO03086383(A8) 申请公布日期 2004.02.12
申请号 WO2003EP03785 申请日期 2003.04.11
申请人 MULTHOFF, GABRIELE 发明人 MULTHOFF, GABRIELE
分类号 A61K31/337;A61K31/475;A61P35/00;(IPC1-7):A61K31/337 主分类号 A61K31/337
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