发明名称 |
Pharmacologic, therapeutic and diagnostic regulation of FGF-1 export |
摘要 |
This invention relates to the regulation of FGF-1 export. In addition, this invention provides methods of regulating the export of FGF-1 from the cell membrane, which methods include regulating the Syn-1 molecule to affect the formation of the FGF-1:Syn-1 complex, regulating the enzyme or protease which cleaves Syn-1 in the FGF-1:Syn-1 complex to effect the release of FGF-1 from the cell membrane, or regulating the FGF-1:Syn-1 complex itself at or near the cell membrane. The invention also provides compositions related to the regulation of FGF-1 export.
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申请公布号 |
US2004028680(A1) |
申请公布日期 |
2004.02.12 |
申请号 |
US20030353458 |
申请日期 |
2003.01.29 |
申请人 |
MAINE MEDICAL RESEARCH CENTER |
发明人 |
MACIAG THOMAS;BURGESS WILSON H.;TARANTINI FRANCESCA;GAMBLE SUSAN;JACKSON ANTHONY Q.;HAMPTON BRIAN |
分类号 |
A61K38/00;A61K38/17;C07K14/47;C07K14/50;C07K16/18;(IPC1-7):A61K39/395 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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