发明名称 |
Medicinal uses of mu-opioid receptor agonists |
摘要 |
The present invention provides methods for stimulating a mu-opioid receptor agonist peptide in a mammal in need thereof. The methods comprise administering to the mammal an effective amount of a selective mu-opioid receptor agonist peptide that comprises at least two alpha-amino acid residues. At least one of the amino acid residues has a positive charge. The amino acid residue in the first position is a tyrosine or tyrosine derivative. The amino acid in the second position is a D-alpha-amino acid. The present invention also provides methods of treating a mammal suffering from conditions or diseases by administering to the mammal an effective amount of the peptides.
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申请公布号 |
US2004029796(A1) |
申请公布日期 |
2004.02.12 |
申请号 |
US20030333485 |
申请日期 |
2003.08.25 |
申请人 |
SZETO HAZEL;SCHILLER PETER W |
发明人 |
SZETO HAZEL;SCHILLER PETER W |
分类号 |
A61K38/07;A61K38/08;A61K38/12;(IPC1-7):A61K38/06 |
主分类号 |
A61K38/07 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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