发明名称 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors
摘要 <p><CHEM> <??>Compounds of Formula (1), Formula (2) or Formula (3) where X is O, S, or (CR1R1)n where n is 0, 1, or 2; Y is a bivalent radical having Formula (4) or Formula (5) where o is an integer from 1 to 4 or Y is a bivalent aryl or 5 or 6 membered heteroaryl radical having to 3 heteroatoms selected from N, S and O, said aryl or heteroaryl groups being unsubstituted, or substituted with 1 to 3 C1-6 alkyl or with 1 to 3 C1-6 fluoroalkyl groups; and the remaining symbols have the meaning described in the specification, have RXR selective retinoid agonist-like activity.</p>
申请公布号 EP1388534(A2) 申请公布日期 2004.02.11
申请号 EP20030025774 申请日期 1999.09.20
申请人 ALLERGAN, INC. 发明人 VULIGONDA, VIDYASAGAR;TSANG, KWOK YIN;VASUDEVAN, JAYASREE;CHANDRARATNA, ROSHANTHA A.
分类号 A61K31/201;A61K31/231;A61K31/352;A61P1/00;A61P3/02;A61P3/06;A61P5/06;A61P9/00;A61P11/00;A61P17/00;A61P17/04;A61P17/06;A61P17/10;A61P17/14;A61P17/16;A61P25/16;A61P25/28;A61P27/02;A61P35/00;A61P37/02;A61P43/00;C07C57/48;C07C57/50;C07C69/00;C07C69/618;C07D311/58;(IPC1-7):C07C57/50 主分类号 A61K31/201
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