发明名称 |
1,4-dihydropyridine-5-carboxylic acid ester derivatives and method for the preparation thereof |
摘要 |
The present invention relates to ester derivatives of 1,4-dihydropyridine-5-carboxylic acid of formula (I) wherein R1, R2 and R3 may be a coumarin group. These compounds possess an anti-viral activity. Most of the anti-viral compounds known in the art are nucleoside-derivatives. Various viruses become resistent against these. Because the compounds according to the invention are not nucleoside-derivatives, they form a suitable alternative. The invention also relates to a method of preparing the anti-viral substances according to the invention.
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申请公布号 |
US6689799(B1) |
申请公布日期 |
2004.02.10 |
申请号 |
US20020069216 |
申请日期 |
2002.06.06 |
申请人 |
REPHARTOX |
发明人 |
STERK GEERT JAN;VAN DER WERF JAN FETZE |
分类号 |
C07D405/12;(IPC1-7):A61K31/44;C07D405/00 |
主分类号 |
C07D405/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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