发明名称 DRUG CONJUGATES AND THEIR USE FOR TREATING CANCER, AN AUTOIMMUNE DISEASE OR AN INFECTIOUS DISEASE
摘要 Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptide-based Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug compounds are also disclosed. Metho ds for treating cancer, an autoimmune disease or an infectious disease using th e compounds and compositions of the invention are also disclosed.
申请公布号 CA2494105(A1) 申请公布日期 2004.02.05
申请号 CA20032494105 申请日期 2003.07.31
申请人 SEATTLE GENETICS, INC. 发明人 TOKI, BRIAN E.;DORONINA, SVETLANA;SENTER, PETER D.
分类号 A61K47/48;A61P35/00;C12P21/08 主分类号 A61K47/48
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