发明名称 |
DRUG CONJUGATES AND THEIR USE FOR TREATING CANCER, AN AUTOIMMUNE DISEASE OR AN INFECTIOUS DISEASE |
摘要 |
Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptide-based Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug compounds are also disclosed. Metho ds for treating cancer, an autoimmune disease or an infectious disease using th e compounds and compositions of the invention are also disclosed. |
申请公布号 |
CA2494105(A1) |
申请公布日期 |
2004.02.05 |
申请号 |
CA20032494105 |
申请日期 |
2003.07.31 |
申请人 |
SEATTLE GENETICS, INC. |
发明人 |
TOKI, BRIAN E.;DORONINA, SVETLANA;SENTER, PETER D. |
分类号 |
A61K47/48;A61P35/00;C12P21/08 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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