摘要 |
PROBLEM TO BE SOLVED: To obtain an aqueous composition comprising tezacitabine and having good storage stability. SOLUTION: This composition comprises (a) water, (b) the tezacitabine and (c) a buffer for maintaining the pH of the composition at about 7 or above. The buffer for adjusting the pH is selected from the group consisting of TRIS (2-amino-2-hydroxymethyl-1,3-propanediol), glycine, a glutamate and a phosphate. The composition has a pH 8-11, preferably 8.5-10.0. COPYRIGHT: (C)2004,JPO
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