| 摘要 |
A compound of the formula (I): wherein A is alkylene optionally having an unsaturated bond; R is -C(=O)-R<1>; R<1 >is hydroxy or the like; m is 0 or 1; p is 0 or 1; X<1 >and X<3 >are each independently optionally substituted aryl or optionally substituted heteroaryl or the like; X<2 >is a bond, -CH2-, -S-, -SO2-, -CH2-O-, -O-CH2-, -CH2-S-, -S-CH2-, or the like; X<4 >is -CH2-, -CH2-CH2-, -C(=O)-, or the like, having a dual antagonistic activity against both a thromboxane A2 receptor and a prostaglandin D2 receptor is found.
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