发明名称 NEW CRYSTAL FORM OF CEFDINIR
摘要 PROBLEM TO BE SOLVED: To provide a new crystal form of cefdinir which has a higher stability and lower solubility than those of cefdinyl of a publicly known crystal form. SOLUTION: This new crystal form of cefdinir exhibiting a specific X-ray diffraction spectrum is obtained by adding at least 1 kind of an organic solvent to an aqueous cefdinir solution up to 10 vol/vol %, cooling the solution to a temperature between 0°C-(+)6°C, decreasing pH until between 1.5-3 for precipitating the crystal and isolating the same by a publicly known technique. COPYRIGHT: (C)2004,JPO
申请公布号 JP2004035543(A) 申请公布日期 2004.02.05
申请号 JP20030101096 申请日期 2003.04.04
申请人 ACS DOBFAR SPA 发明人 MANCA ANTONIO;SALA BRUNO;MONGUZZI RICCARDO
分类号 C07D501/22;A61K31/546;A61P31/04;C07D501/00;C07D501/14;(IPC1-7):C07D501/22 主分类号 C07D501/22
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