METHOD FOR INCREASING INSULIN SENSITIVITY AND FOR TREATING AND PREVENTING TYPE 2 DIABETES

摘要

It is disclosed here that insulin sensitivity in a human or non-human animal can be increased by reducing stearoyl-CoA desaturase-1 (SCD 1) activity in t he animal. This provides a new tool for treating and preventing type 2 diabetes . Also disclosed are methods for identifying agents that can increase insulin sensitivity in a human or non-human animal through determining the agents' effects on SCD1 activity.