发明名称 |
Nasal spray formulation and method |
摘要 |
A nasal spray formulation for use in female contraception or in the treatment of benign gynecological disorders is described. The nasal preparation is comprised of a GnRH compound and an estrogenic compound in the form of a water-soluble complex with a water-soluble cyclodextrin. The preparation effectively suppresses ovarian estrogen and progesterone production, and prevents signs and symptoms of estrogen deficiency, without a significant increase in the risk of endometrial hyperplasia.
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申请公布号 |
US2004022739(A1) |
申请公布日期 |
2004.02.05 |
申请号 |
US20020298378 |
申请日期 |
2002.11.15 |
申请人 |
DANIELS JOHN R.;PIKE MALCOLM C.;SPICER DARCY V.;DANIELS ANNAMARIE |
发明人 |
DANIELS JOHN R.;PIKE MALCOLM C.;SPICER DARCY V.;DANIELS ANNAMARIE |
分类号 |
A61K9/00;A61K31/565;A61K31/724;A61K38/24;A61K47/40;(IPC1-7):A61K38/24;A61K31/56;A61L9/04 |
主分类号 |
A61K9/00 |
代理机构 |
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