ANTAGONIST OF MELANIN-CONCENTRATING HORMONE RECEPTOR COMPRISING BENZIMIDAZOLE DERIVATIVE AS ACTIVE INGREDINT

摘要

Benzimidazole derivative of the general formula: [I] wherein each of B<1>, B<2> and B<3> represents a hydrogen atom or a lower alkyl; R<1> and R<2> may be identical with or different from each other and represent lower alkyls, etc.; each of R<3> and R<4> represents a hydrogen atom, etc.; W represents a 3 to 8-membered aromatic or aliphatic heterocycle, etc.; and Ar represents a substituted or unsubstituted aromatic heterocycle, etc. This compound functions as an antagonist of melanin-concentrating hormone receptor and is useful as a drug for central diseases, circulatory diseases and metabolic diseases.