| 发明名称 |
Lipids |
| 摘要 |
Bipolar lipids are described which are able to form complexes with polyanions. The lipids comprise a cationic head linked to a hydrophobic backbone and a hydrophilic tail and are capable of self assembly to form stable complexes in aqueous solutions. The lipids are of particular use for the delivery of bioactive substances such as nucleic acids to cells in vitro and especially in vivo.
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| 申请公布号 |
US2004024220(A1) |
申请公布日期 |
2004.02.05 |
| 申请号 |
US20030434091 |
申请日期 |
2003.05.09 |
| 申请人 |
CELLTECH R & D LIMITED |
发明人 |
EATON MICHAEL ANTHONY WILLIAM;NORMAN TIMOTHY JOHN;PARKER DAVID;BAKER TERENCE SEWARD;WEIR ANDREW NEIL CHARLES;CATTERALL CATHERINE FIONA |
| 分类号 |
A61K47/30;A61K31/16;A61K38/00;A61K45/00;A61K47/48;A61K49/00;A61P43/00;C07C235/10;C07C235/12;C07C237/10;C07C271/20;(IPC1-7):C07D211/82;C07D213/54;C07D207/34;C07C229/00 |
主分类号 |
A61K47/30 |
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