发明名称 |
Delivery of molecules and complexes to mammalian cells in vivo |
摘要 |
Disclosed is a system for providing in vivo delivery of molecules or complexes to extravascular mammalian cells using an intravascular administration route. The molecules or complexes are inserted in an injection solution into a mammalian vasculature. Insertion of the injection solution at an appropriate rate transiently increases the volume of extravascular fluid in the tissue thereby facilitating delivery of the molecule to the cell.
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申请公布号 |
US2004023850(A1) |
申请公布日期 |
2004.02.05 |
申请号 |
US20030628792 |
申请日期 |
2003.07.28 |
申请人 |
WOLFF JON A.;BUDKER VLADIMIR G.;HERWEIJER HANS;HAGSTROM JAMES E.;MONAHAN SEAN D.;HEGGE JULIA;SUBBOTIN VLADIMIR |
发明人 |
WOLFF JON A.;BUDKER VLADIMIR G.;HERWEIJER HANS;HAGSTROM JAMES E.;MONAHAN SEAN D.;HEGGE JULIA;SUBBOTIN VLADIMIR |
分类号 |
A61K38/00;A61M;A61M1/00;(IPC1-7):A61K38/00 |
主分类号 |
A61K38/00 |
代理机构 |
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地址 |
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