发明名称 |
Method for purifying teicoplanin A2 |
摘要 |
Disclosed is a method for purifying teicoplanin A2 comprising: (i) a primary pre-purification step of purifying a filtrate of fermentation broth of a strain using a synthetic adsorbent; (ii) a secondary pre-purification step of purifying the primary pre-purification solution using a cation exchange resin having a high cross-linkage, a catalytic resin or a chelate resin; (iii) a final purification step of purifying the secondary pre-purification solution using a reversed phase resin; and (iv) a powder-forming step. According to the present invention, it is possible to obtain teicoplanin A2 with a higher purity through a relatively simple process without using an excessive amount of an organic solvent.
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申请公布号 |
US2004024177(A1) |
申请公布日期 |
2004.02.05 |
申请号 |
US20030621353 |
申请日期 |
2003.07.18 |
申请人 |
CKD BIO CORP. |
发明人 |
KANG TAE-WON;CHOI BYOUNG-TAEK;CHOI GANG-SUN;CHOI YOUNG-RACK;HWANG SUNG-HO |
分类号 |
C07K9/00;(IPC1-7):C07K9/00;A61K38/14 |
主分类号 |
C07K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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