| 发明名称 |
CELL CULTURE SYSTEM FOR SYNTHESIS OF INFECTIOUS HEPATITIS C VIRUS |
| 摘要 |
The invention relates to a hepatitis C virus (HCV) cDNA-based culture system capable of synthesis of infectious HCV in cell culture and cell-to-cell spread of the virus. The invention also relates to a method of measuring the level of HCV infection in a hepatocyte cell. A method for identifying a modulator of HCV activity is also presented, and a method for modulating HCV activity. The invention provides a reliable system for both genetic analysis of the viral genome and for the development of novel antiviral str ategies. |
| 申请公布号 |
WO02072776(A3) |
申请公布日期 |
2004.02.05 |
| 申请号 |
WO2002US07516 |
申请日期 |
2002.03.11 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;DASGUPTA, ASIM;KOKA, PRASAD, S. |
发明人 |
DASGUPTA, ASIM;KOKA, PRASAD, S. |
| 分类号 |
G01N33/50;A61K31/7088;A61K38/00;A61K45/00;A61P31/14;C07K14/18;C12N7/00;C12N15/09;C12P21/04;C12Q1/04;C12Q1/24;C12Q1/68;G01N33/15;G01N33/576;G01N33/68 |
主分类号 |
G01N33/50 |
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