METHOD OF INFERRING DIPLOTYPE CONFIGURATION FROM THE GENOTYPE OF INDIVIDUAL

摘要

Haplotype frequencies of a population were calculated from the genotypic information of each subject to.determine the diplotype distribution based on the haplotype frequencies and genotypic information. A diplotype configuration of an individual can be inferred from the diplotype distribution. Furthermore, the inferred diplotype configuration enables one to calculate the probability of an individual to exhibit a specific phenotype, the probability of a specific drug being effective or having side effects in an individual, etc.