| 发明名称 |
Life attenuated European PRRS virus, nucleotide sequence coding said virus, method of generating such virus, cell line, and a pharmaceutical composition comprising said PRRS viruses and the use thereof |
| 摘要 |
<p>The present invention realtes to live attenuated European PRRS viruses which are attenuated by nucleic acid mutations on specific sties of the viral protein coded by ORF 2, 3 and 5. The invention also pertains to nucleotide sequences coding said viruses, methods of generating such viruses and a pharmaceutical composition comprising said PRRS viruses and teh use of said PRRS virus in the manufacture of a vaccine for the prophylaxis and treatment of PRRSV infections.</p> |
| 申请公布号 |
SK11282003(A3) |
申请公布日期 |
2004.02.03 |
| 申请号 |
SK20030001128 |
申请日期 |
2002.03.07 |
| 申请人 |
BOEHRINGER INGELHEIM VETMEDICA GMBH |
发明人 |
ELBERS KNUT;PESCHKE STEFAN;SCHUETZ BETTINA |
| 分类号 |
C12N15/09;A61K39/12;A61K39/15;A61P11/00;A61P15/00;C07K14/08;C12N5/10;C12N7/00;C12N7/04;C12N7/08;C12N15/40;(IPC1-7):C12N7/04;C12N7/06 |
主分类号 |
C12N15/09 |
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