| 摘要 |
The present invention provides a variety of methods that are based on stereoselective epoxidation of an olefin by an epoxidizing agent derived from a reaction between an oxidizing agent and a chiral ketone. For example, present invention provides methods for producing an epoxide from an olefin, for increasing a relative concentration of at least one stereoisomer of an olefin, and for stereoselectively producing an alpha-acyloxy carbonyl compound. Preferably, the chiral ketone is of the formula:or a derivative thereof which is capable of converting to the chiral ketone of Formula I under the reaction conditions, where a, b, n, X, R<1>, R<2>, R<3>, R<4>, R<5 >and R<6 >are those defined herein.
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