发明名称 |
Lipooligosaccharide based vaccine for prevention of moraxella (branhamella)catarrhalis infections in humans |
摘要 |
A conjugate vaccine for Moraxella (Branhamella) catarrhalis comprising isolated lipooligosaccharide from which esterified fatty acids have been removed, to produce a detoxified lipooligosaccharide (dLOS), or from which lipid A has been removed, to produce a detoxified oligosaccharide (OS), which is linked to an immunogenic carrier. The vaccine is useful for preventing otitis media and respiratory infections caused by M. catarrhalis in mammals, including humans.
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申请公布号 |
US6685949(B1) |
申请公布日期 |
2004.02.03 |
申请号 |
US20000610034 |
申请日期 |
2000.07.05 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH & HUMAN SERVICES |
发明人 |
GU XIN-XING;ROBBINS JOHN B. |
分类号 |
C12P19/04;(IPC1-7):A61K39/02;A01N65/00;A61K39/00;C12P19/00;C12P19/18 |
主分类号 |
C12P19/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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