P-GLYCOPROTEIN INHIBITOR COMPRISING OTILONIUM BROMIDE AS EFFECTIVE INGREDIENT

摘要

PURPOSE: Provided is a p-glycoprotein inhibitor which comprises otilonium bromide as an effective ingredient, thereby increasing the absorption of otilonium bromide into the cell and bioavailability of the drug in the living body. CONSTITUTION: A p-glycoprotein inhibitor is characterized by comprising, as an effective ingredient, otilonium bromide that inhibits the activity of p-glycoprotein and increases the absorption of drugs into the cell. The composition is formulated into a sustained release preparation and releases drugs continuously for 12 hours.