发明名称 BIPHENYLSUPHONYLAMIDIC INHIBITORS OF INTERCELLULAR PROTEASE
摘要 Compounds of formula (I) wherein R<1> includes alkyl, halo, nitro, amino, cyano, alkoxy, and alkoxycarbonyl; R<2> is alkyl and substituted alkyl; and R<3> is OH or NHOH, are useful for inhibiting matrix metalloproteinase enzymes in animals, and as such, prevent and treat diseases resulting from the breakdown of connective tissues.
申请公布号 PL186416(B1) 申请公布日期 2004.01.30
申请号 PL19970329929 申请日期 1997.04.24
申请人 WARNER-LAMBERT CO. 发明人 O'BRIEN PATRICK M.;SLISKOVIC DRAGO R.
分类号 A61K31/18;A61K31/00;A61K31/195;A61K31/215;A61K31/216;A61P9/00;A61P9/10;A61P19/00;A61P19/02;A61P43/00;C07C311/19;C07C311/29;C07C311/37;C07C311/42 主分类号 A61K31/18
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