| 发明名称 |
PURIFICATION OF HBV ANTIGENS FOR USE IN VACCINES |
| 摘要 |
<p>The present invention relates to a method for the production of hepatitis B antigen stable for use in a vaccine, the method comprising purification of the antigen in the presence of cysteine, to vaccines comprising such antigens. 27 claims</p> |
| 申请公布号 |
BG107545(A) |
申请公布日期 |
2004.01.30 |
| 申请号 |
BG20030107545 |
申请日期 |
2003.02.07 |
| 申请人 |
GLAXO SMITHKLINE BIOLOGICALS S.A. |
发明人 |
DE HEYDER, KOEN;SCHU, PETER;SERANTONI, MICHELLE;VAN OPSTAL, OMER |
| 分类号 |
A61K39/29;A61K38/00;A61K39/00;A61K39/295;A61K39/39;C07K1/14;C07K14/02;(IPC1-7):C07K14/02;C07K1/36 |
主分类号 |
A61K39/29 |
| 代理机构 |
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