发明名称 |
POLY (POTASSIUM AND SODIUM STYRENE SULFONATE), ITS MANUFACTURE AND ITS USES |
摘要 |
Antibiotic-associated diarrhea, such as that caused by Clostridium difficile , represents a serious medical complication that can result from administering a broad~spectrum antibiotic to a subject. Such diarrhea leads to significant potassium loss from the subject. The present invention discloses a polymeric therapeutic agent that treats antibiotic-associated diarrhea and is physiologically potassium neutral. This polymer contains polystyrene sodium sulfonate and polystyrene potassium sulfonate repeat units. |
申请公布号 |
CA2492211(A1) |
申请公布日期 |
2004.01.29 |
申请号 |
CA20032492211 |
申请日期 |
2003.07.18 |
申请人 |
GENZYME CORPORATION |
发明人 |
CHORGHADE, MUKUND S.;CHANCELLOR-ADAMS, TONI G.;KURTZ, CAROLINE I. BACON;KATTI, SANJEEV S.;MHASKAR, SUNIL V.;BHAGAT, HITESH R. |
分类号 |
A61K31/74;A61K31/795;C08F8/34;C08F8/36;C08L25/18 |
主分类号 |
A61K31/74 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|