A method for detecting one or more pathogens in a subject. The method includes the steps of : (a) procuring a biological sample, wherein the biological sample comprises nucleic acid material; (b) amplifying the nucleic acid material using random primers to produce a set of random amplicons; (c) providing one or more pathogen-specific probes or probe sets; (d) hybridizing the set of random amplicons with the one or more pathogen-specific probes or probe sets; and (e) determining selective hybridization between a random amplicon and a pathogen-specific probe or probe set, whereby the presence of a pathogen in a biological sample is detected.
申请公布号
WO03087297(A3)
申请公布日期
2004.01.29
申请号
WO2002US25118
申请日期
2002.08.08
申请人
NORTH CAROLINA STATE UNIVERSITY;SHARP, NICHOLAS, J., H.;SCHATZBERG, SCOTT, J.;OBRIAN, GREGORY, ROBERT
发明人
SHARP, NICHOLAS, J., H.;SCHATZBERG, SCOTT, J.;OBRIAN, GREGORY, ROBERT