| 发明名称 |
Sigma receptor ligands and their medical uses |
| 摘要 |
The present invention is based on the finding that sigma receptor ligands can modulate endothelial cell proliferation and/or survival, and hence control angiogenesis, and in particular that sigma receptor ligand antagonists can be used to inhibit angiogenesis aid so treat conditions such as psoriasis, diabetic retinopathy and cancer. Exemplary compounds include IPAG and rimcazole.
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| 申请公布号 |
US2004019060(A1) |
申请公布日期 |
2004.01.29 |
| 申请号 |
US20030240327 |
申请日期 |
2003.06.05 |
| 申请人 |
SPRUCE BARBARA ANN;ECCLES SUZANNE AMY;DEXTER MICHAEL |
发明人 |
SPRUCE BARBARA ANN;ECCLES SUZANNE AMY;DEXTER MICHAEL |
| 分类号 |
A61K31/00;A61K31/155;A61K31/439;A61K31/445;A61K31/496;A61K45/00;A61P1/04;A61P9/00;A61P9/10;A61P15/00;A61P17/00;A61P17/06;A61P27/00;A61P27/02;A61P35/00;A61P35/04;A61P43/00;G01N33/15;G01N33/50;(IPC1-7):A61K31/496 |
主分类号 |
A61K31/00 |
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