| 发明名称 |
BICYCLIC PIPERIDINE DERIVATIVES AS ANTAGONISTS OF THE CCR1 CHEMOKINE RECEPTOR |
| 摘要 |
<p>A compound of the formula (I) wherein a, b, cR<1>, R<2>, R<3>, R<4>, R<5>, R<6>, Q, W, Y, and Z are defined as above, useful as potent and selective inhibitors of MIP-1alpha(CCL3) binding to its receptor CCR1 found on inflammatory and immunomodulatory cells (preferably leukocytes and lymphocytes).</p> |
| 申请公布号 |
WO2004009588(A1) |
申请公布日期 |
2004.01.29 |
| 申请号 |
WO2003IB03155 |
申请日期 |
2003.07.07 |
| 申请人 |
PFIZER PRODUCTS INC.;BLUMBERG, LAURA, COOK;BROWN, MATTHEW, FRANK;HAYWARD, MATTHEW, MERRILL;POSS, CHRISTOPHER, STANLEY |
发明人 |
BLUMBERG, LAURA, COOK;BROWN, MATTHEW, FRANK;HAYWARD, MATTHEW, MERRILL;POSS, CHRISTOPHER, STANLEY |
| 分类号 |
A61K31/439;A61K31/46;A61K31/5377;A61K31/538;A61K31/55;A61P1/04;A61P1/14;A61P1/16;A61P3/04;A61P3/06;A61P7/00;A61P9/10;A61P9/14;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/06;A61P31/08;A61P31/10;A61P31/18;A61P31/20;A61P31/22;A61P33/06;A61P35/04;A61P37/02;A61P37/06;A61P37/08;C07D451/04;C07D451/06;C07D451/14;(IPC1-7):C07D451/06 |
主分类号 |
A61K31/439 |
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